• Cofactor
  • Cofactor
  • Cofactor
  • Cofactor
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Elysium Health

Cofactor

Cofactor

$75.00 USD
$75.00 USD
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Youthful skin requires collagen and NAD+. Unfortunately, both decline with age, starting in our 20s. Cofactor by Elysium Health is an advanced 4-in-1 collagen system that combines: bioactive collagen peptides, nicotinamide riboside (NR), a precursor that’s clinically proven to boost NAD+, hyaluronic acid, and vitamin C.

  • Collagen peptides (grass fed) to stimulate and provide the building blocks for collagen production
  • NAD+ booster NR to promote cellular youth for optimal collagen production
  • Hyaluronic Acid to improve skin elasticity, hydration, and barrier function
  • Vitamin C to support collagen production
  • Reduce fine lines and wrinkles
  • Bone, joint, hair, and nail support
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Collagen production requires youthful cells

NAD+ is a critical coenzyme found in every cell in your body that helps keep cells youthful and functioning optimally. As we age, our NAD+ levels naturally decline. In skin, NAD+ levels decline by almost 60% between young adulthood and middle age, impacting collagen production—by age 40, we’ve lost about 25% of our collagen.

Cofactor provides an advanced 4-in-1 collagen system that combines: collagen peptides, which provide the stimulus and the building blocks for collagen; nicotinamide riboside, a clinically proven NAD+ booster, to help improve the health and function of the cells that use these building blocks to produce collagen; hyaluronic acid to improve skin hydration and elasticity; and vitamin C, an essential cofactor for collagen synthesis.

Better skin, hair, nails—and more

Human clinical studies demonstrate that supplementation with collagen peptides significantly increases skin elasticity and dermal density (a reflection of the amount of structural components like collagen and elastin in the dermis) and improves wrinkles, skin roughness, and cellulite scores. Collagen peptides have also been shown to support healthy hair and nail growth. Hyaluronic acid, another key ingredient in Cofactor, has been clinically proven to increase skin moisture levels, boost elasticity, and improve skin barrier function.

See the science

Supercharge your collagen system by combining Cofactor with Mosaic

Elysium’s skin aging and collagen support supplement,Mosaic, fights oxidative stress from sun exposure and aging—the main culprit in collagen loss. Combine Cofactor with Mosaic to supercharge your collagen system by protecting the collagen you’re replacing with Cofactor.

Bone and joint benefits for healthy mobility

As the most abundant protein throughout our bodies, collagen is the primary building block for the body’s connective tissues, such as bones, tendons, ligaments, and cartilage, playing a key role in supporting our strength, flexibility, and movement. Human clinical studies show that oral supplementation with collagen peptides improves markers of bone health, including bone mineral density (in postmenopausal women), and supports joint mobility and comfort.

Basis 101: The Science

  • Here's what happens when you take Cofactor, starting at 3 weeks.

    Explore the benefits of Elysium’s advanced collagen support system, Cofactor, from three weeks to one year and beyond.

  • What happens to collagen with age?

    Collagen keeps your skin resilient, plump, and youthful. Learn why it changes with age and what you can do to slow its decline.

  • Cofactor in the kitchen: serious science, simple recipes

    Looking for delicious ways to incorporate Cofactor in your daily routine? Here are some of the Elysium team’s favorite ways to take Cofac...

Frequently Asked Questions

What is Cofactor and what does it do?

Cofactor is a 4-in-1 collagen support system combining collagen peptides, nicotinamide riboside (a clinically proven NAD+ booster), hyaluronic acid for skin hydration and elasticity, and vitamin C for collagen synthesis.

Why does Cofactor contain nicotinamide riboside?

Collagen and NAD+ both decline starting in our 20s. NAD+ decline reduces cellular function and collagen production. Cofactor combines collagen peptides with nicotinamide riboside (NR), clinically proven to boost NAD+, creating an optimal environment for sustained collagen production.

What does hyaluronic acid do?

Hyaluronic acid maintains skin hydration. With age, HA production decreases, reducing hydration and elasticity. Clinical studies show oral HA supplementation increases skin moisture, improves barrier function, and increases elasticity.

When should I expect to see benefits?

Clinical studies suggest increased skin hydration around 3 weeks. Skin elasticity improvements at 2 months. Wrinkle and texture improvements at 4 months. Hair and nail benefits reported at 6 months. Individual results may vary.

How does Cofactor taste?

Cofactor is unflavored with minimal taste and aftertaste.

How do I take Cofactor?

Dissolve Cofactor in liquids or foods such as smoothies, juices, yogurt or water. Because NR is sensitive to prolonged high heat, hot beverages should be consumed within 30 minutes. One serving per day is recommended.

Can I combine Cofactor with Basis or Signal?

Yes. Cofactor, Basis and Signal each contain 250 mg of an NAD+ precursor. Clinical studies show daily supplementation up to 2,000 mg NR or 1,000 mg NMN is safe. Basis adds pterostilbene for DNA maintenance. Signal adds SIRT3 Activation Complex for mitochondrial health.

How do subscriptions work?

Prepaid annual plans offer savings and are final sale. Canceling mid-plan still delivers remaining pouches. Monthly subscriptions cost $62/month and can be canceled anytime before the next shipment. Single purchase is $75.

Where do you ship?

Cofactor, Vision, Index and Senolytic Complex ship only to U.S. addresses. Mosaic, Basis, Signal, Matter and Format ship to U.S. and Canada. Newsletter signup provides international availability updates.

When will I receive my product?

Standard shipping delivers in 5–7 business days after shipping. Expedited shipping (additional fee) delivers in 2–3 business days. Processing takes 1–2 business days.